Can We Phenotype Thought? Using Advanced Imaging Techniques to Understand Social Interactions

Read Montgue

Virginia Tech, and University College London


Modern neuroimaging approaches have opened up the possibility of developing biomarkers for a range of psychopathologies. There has been a meteoric rise in the use of economic games and computational models of reward processing to gain new insights into the neural and behavioral underpinnings of healthy and diseased cognition. One value to these new approaches is their quantitative basis and the fact that they may augment traditional psychological approaches to disordered behavior and thought. This talk will highlight these new approaches, the way that they are connected to clinical thinking, and our own efforts to phenotype healthy and diseased cognition using economic games and computational models.




Related papers:

Xiang T, Ray D, Lohrenz T, Dayan P, Montague PR. (2012). Computational Phenotyping of Two-Person Interactions Reveals Differential Neural Response to Depth-of-Thought. PLoS Comput Biol, 8(12). Link


Montague PR. (2012). The Scylla and Charybdis of Neuroeconomic Approaches to Psychopathology. Biological Psychiatry, 72(2):80-81. Link


Montague PR, Dolan RJ, Friston KJ, Dayan P. (2012). Computational Psychiatry. Trends Cogn Sci:Epub 2011 Dec 14(1):72-80.  Link


Koshelev M, Lohrenz T, Vannucci M, Montague PR. (2010). Biosensor approach to psychopathology classification. PLoS Comput Biol, 6(10):e1000966.  Link


Kishida, KT, King-Casas, B, Montague PR. (2010). Neuroeconomic approaches to mental disorders. Neuron, 67(4):543-54. Link